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VIMOVO is a twice-a-day prescription medicine. Taking one VIMOVO pill at night and one pill the next morning can help reduce the pain caused by osteoarthritis while helping to avoid some stomach issues common to NSAIDs.

Taking twice-daily VIMOVO

How to Take VIMOVO

Taking VIMOVO with low-dose aspirin

If you take low-dose aspirin (less than 325 mg/day) for your heart, and also need to take an NSAID, VIMOVO may be a good option for you and your doctor to consider.

However, it's important to be aware that all prescription NSAIDs, including VIMOVO, may increase the chance of heart attack or stroke, which can lead to death. Taking low-dose aspirin may not reduce this risk, and you should never use VIMOVO as a substitute for aspirin in preventing heart attack or stroke. Taking aspirin and an NSAID may increase your risk of side effects, including serious ones. Tell your doctor if you take aspirin.

Following your doctor's instructions

  • Take VIMOVO exactly as your doctor tells you to take it
  • Take VIMOVO at least 30 minutes before a meal
  • Swallow VIMOVO tablets whole with liquid. Do not split, chew, crush, or dissolve the VIMOVO tablet
  • Tell your doctor if you cannot swallow the tablet whole—you may need a different medicine
  • Your doctor may tell you to take vitamin D and calcium supplements during treatment with VIMOVO
  • Your doctor will tell you how many VIMOVO tablets to take and when to take them
  • Do not change your dose or stop VIMOVO without first talking to your doctor
  • You may use antacids while taking VIMOVO
  • If you forget to take a dose of VIMOVO, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take the next dose on time. Do not take two doses at one time to make up for a missed dose
  • If you take more VIMOVO than your doctor recommends, tell your doctor, call the Poison Control Center at 1-800-222-1222, or go to the closest hospital emergency room right away. Symptoms of taking too much VIMOVO may include feeling weak and tired, dizziness, feeling sleepy, upper stomach-area pain or discomfort, heartburn, indigestion or nausea, a change in breathing or stopping breathing, vomiting, bleeding, movements of a body part that you cannot control, coordination problems, and decreased movement

Important Safety Information:

Like all medications that contain nonsteroidal
anti-inflammatory drugs (NSAIDs), VIMOVO may increase the chance of a heart attack or stroke that can lead to death. This chance increases

  • With longer use of NSAID medicines
  • In people who have heart disease
See additional Important Safety Information below.
$0 for one year with the VIMOVO savings card.

Requires a prescription; subject to eligibility rules; restrictions apply.

Check Eligibility

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You are leaving VIMOVO.com

The site you are about to visit is maintained by a third party, who is solely responsible for its contents. Horizon Pharma provides this link as a service to Web site visitors. Horizon Pharma is not responsible for the privacy policy of any third-party Web sites. We encourage you to read the privacy policy of every Web site you visit. Click Cancel to return or OK to continue.

*Eligibility: This offer is good for eligible patients purchasing up to a 30-day (up to 60 tablets) supply of VIMOVO® (naproxen/esomeprazole magnesium) delayed-release tablets and may not be used for any other product. This offer is good for the purchase of VIMOVO manufactured for AstraZeneca Pharmaceuticals LP and lawfully purchased from an authorized retailer or distributor in the United States or its territories. This offer is not insurance and is not valid for mail order or prescriptions purchased under Medicaid, Medicare, or similar federal or state programs, or for patients who are Medicare eligible and enrolled in an employer-sponsored group waiver health plan or government-subsidized prescription drug benefit program for retirees or for patients under 18 years of age. Offer not valid where prohibited by law, taxed, or restricted. Offer is not transferable, is limited to one per person and may not be combined with any other offer. Offer must be presented along with a valid prescription for VIMOVO at the time of purchase.

Offer: If you have commercial insurance, you may pay no out-of-pocket costs at the pharmacy counter. You will receive up to $75 in savings on your out-of-pocket costs per prescription for up to 12 prescription fills. If you pay cash for your prescription, you will receive up to $75 in savings on your out-of-pocket costs for your prescription for up to 12 prescription fills. First use must occur by 03/31/2014. Offer expires 14 months from date of first use. AstraZeneca reserves the right to change or discontinue this offer at any time without notice. If you have any questions regarding this offer, please call 1-877-358-4668.

Pharmacist instructions for a patient with an eligible Third Party: Submit the claim to the primary Third Party Payer first, then submit the balance due to Therapy First Plus as a Secondary Payer as a co-pay only billing using a valid Other Coverage Code (eg, 8). The patient pay amount will be reduced by up to $75.00 and reimbursement will be received from Therapy First Plus.

Pharmacist instructions for a cash-paying patient: Submit this claim to Therapy First Plus. A valid Other Coverage Code (eg, 1) is required. The patient pay amount will be reduced by up to $75.00 and reimbursement will be received from Therapy First Plus.

Valid Other Coverage Code required: For any questions regarding Therapy First Plus online processing, please call the Help Desk at 1-800-422-5604.